Glial promoter selectivity following AAV-delivery to the immature brain
Glial promoter selectivity following AAV-delivery to the immature brain
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Recombinant adeno-associated virus (AAV) vectors are versatile tools for gene transfer to the central nervous system (CNS) and proof-of-concept studies in adult rodents have shown that the use of cell type-specific promoters is sufficient to target AAV-mediated transgene expression to glia. However, neurological disorders caused by glial pathology...
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Full title
Glial promoter selectivity following AAV-delivery to the immature brain
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TN_cdi_plos_journals_1368619986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1368619986
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065646
