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LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1369309083

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

About this item

Full title

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-06, Vol.8 (6), p.e65763

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that represents a promising target for the treatment of several metabolic diseases. Administration of recombinant wild type FGF21 to diabetic animals leads to a dramatic improvement in glycaemia and ameliorates other systemic measures of metabolic health. Here we report the pharmaco...

Alternative Titles

Full title

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1369309083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1369309083

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0065763

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