Mice with Hypomorphic Expression of the Sodium-Phosphate Cotransporter PiT1/Slc20a1 Have an Unexpect...
Mice with Hypomorphic Expression of the Sodium-Phosphate Cotransporter PiT1/Slc20a1 Have an Unexpected Normal Bone Mineralization
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The formation of hydroxyapatite crystals and their insertion into collagen fibrils of the matrix are essential steps for bone mineralization. As phosphate is a main structural component of apatite crystals, its uptake by skeletal cells is critical and must be controlled by specialized membrane proteins. In mammals, in vitro studies have suggested t...
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Mice with Hypomorphic Expression of the Sodium-Phosphate Cotransporter PiT1/Slc20a1 Have an Unexpected Normal Bone Mineralization
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TN_cdi_plos_journals_1371456490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371456490
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065979