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Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expressi...

Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expressi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371831056

Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels

About this item

Full title

Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-06, Vol.8 (6), p.e67855-e67855

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The functions of actin family members during development are poorly understood. To investigate the role of beta-actin in mammalian development, a beta-actin knockout mouse model was used. Homozygous beta-actin knockout mice are lethal at embryonic day (E)10.5. At E10.25 beta-actin knockout embryos are growth retarded and display a pale yolk sac and...

Alternative Titles

Full title

Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1371831056

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1371831056

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0067855

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