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Dynamics of the Full Length and Mutated Heat Shock Factor 1 in Human Cells

Dynamics of the Full Length and Mutated Heat Shock Factor 1 in Human Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1426970577

Dynamics of the Full Length and Mutated Heat Shock Factor 1 in Human Cells

About this item

Full title

Dynamics of the Full Length and Mutated Heat Shock Factor 1 in Human Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-07, Vol.8 (7), p.e67566-e67566

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress. Upon stress, HSF1 binds to and transcribes hsp genes and repeated satellite III (sat III) sequences present at the 9q12 locus. HSF1 binding to pericentric sat III sequences forms structures k...

Alternative Titles

Full title

Dynamics of the Full Length and Mutated Heat Shock Factor 1 in Human Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1426970577

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1426970577

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0067566

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