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Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppres...

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppres...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427353709

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

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Full title

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-07, Vol.8 (7), p.e69240-e69240

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a long history of uses for the treatment of multiple diseases, including cancers. However, the precise mechanisms of actions of BBR in human lung cancer cells remain unclear. In this study, we investigated the molecular mechanisms by which BBR inhibits cell growth...

Alternative Titles

Full title

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1427353709

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427353709

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0069240

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