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PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427353812

PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

About this item

Full title

PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2013-06, Vol.9 (6), p.e1003531

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however, the basis for the anti-metastasic activities resulting from PARP inhibition remains unknown. PARP inhibitors may also act as modulators of tumor angiogenesis. Proteomic analysis of endothelial...

Alternative Titles

Full title

PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1427353812

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1427353812

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1003531

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