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Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpC...

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpC...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1428807373

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM

About this item

Full title

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-08, Vol.8 (8), p.e71836

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is highly and frequently expressed in carcinomas and (cancer-)stem cells, and which plays an important role in the regulation of stem cell pluripotency. We show here that murine EpCAM (mEpCAM) is subject to regulated intramembrane proteolysis in various cells including e...

Alternative Titles

Full title

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1428807373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1428807373

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0071836

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