Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy
Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Both physiological and psychological stress cause thymic atrophy via glucocorticoïd (GC)-dependent apoptosis of double-positive (DP) thymocytes. Given the pervasiveness of stress, GC-induced thymic atrophy is arguably the most common type of acquired immunodeficiency. We recently reported that interleukin-21 (IL-21) has a unique ability to expand t...
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Full title
Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy
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TN_cdi_plos_journals_1429411642
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1429411642
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0072801