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Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1429411642

Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

About this item

Full title

Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013, Vol.8 (9), p.e72801-e72801

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Both physiological and psychological stress cause thymic atrophy via glucocorticoïd (GC)-dependent apoptosis of double-positive (DP) thymocytes. Given the pervasiveness of stress, GC-induced thymic atrophy is arguably the most common type of acquired immunodeficiency. We recently reported that interleukin-21 (IL-21) has a unique ability to expand t...

Alternative Titles

Full title

Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1429411642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1429411642

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0072801

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