Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Ce...
Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous malignant melanoma and the presence of autoantibodies that label neurons in the inner retina. The visual symptoms and electroretinogram (ERG) phenotype characteristic of MAR resemble the congenital visual disease caused by mutations in TRPM1, a cation chann...
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Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice
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TN_cdi_plos_journals_1430168683
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430168683
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0069506
