Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Surviva...
Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Nucleotide excision repair (NER) orchestrates the repair of helix distorting DNA damage, induced by both ultraviolet radiation (UVR) and cisplatin. There is evidence that the global genome repair (GGR) arm of NER is dysfunctional in melanoma and it is known to have limited induction in melanoma cell lines after cisplatin treatment. The aims of this...
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Full title
Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma
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TN_cdi_plos_journals_1430170945
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430170945
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0070424
