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GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/M...

GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/M...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430235526

GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/MAPK-dependent mechanism

About this item

Full title

GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/MAPK-dependent mechanism

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-08, Vol.8 (8), p.e72404

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lipopolysaccharide (LPS) is a critical factor for inducing acute lung injury. GATA-2, a transcription factor, contributes to the control of cell activity and function. Exposure of RAW 264.7 cells to LPS induced interleukin (IL)-1β mRNA and protein expression and GATA-2 translocation from the cytoplasm to nuclei in concentration- and time-dependent...

Alternative Titles

Full title

GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/MAPK-dependent mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1430235526

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430235526

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0072404

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