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Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-ne...

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430782458

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis)

About this item

Full title

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis)

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2013-07, Vol.7 (7), p.e2306-e2306

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The endothelial protein C receptor (EPCR) enhances anticoagulation by accelerating activation of protein C to activated protein C (APC) and mediates anti-inflammatory effects by facilitating APC-mediated signaling via protease activated receptor-1. We studied the role of EPCR in the host response during pneumonia-derived sepsis instigated by Burkho...

Alternative Titles

Full title

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1430782458

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1430782458

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0002306

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