Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA meth...
Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation
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Author / Creator
Paliwal, Anupam , Temkin, Alexis M , Kerkel, Kristi , Yale, Alexander , Yotova, Iveta , Drost, Natalia , Lax, Simon , Nhan-Chang, Chia-Ling , Powell, Charles , Borczuk, Alain , Aviv, Abraham , Wapner, Ronald , Chen, Xiaowei , Nagy, Peter L , Schork, Nicholas , Do, Catherine , Torkamani, Ali and Tycko, Benjamin
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data....
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Full title
Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation
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TN_cdi_plos_journals_1433014020
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433014020
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003622
