GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic...
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
About this item
Full title
Author / Creator
Bottolo, Leonardo , Chadeau-Hyam, Marc , Hastie, David I. , Zeller, Tanja , Liquet, Benoit , Newcombe, Paul , Yengo, Loic , Wild, Philipp S. , Schillert, Arne , Ziegler, Andreas , Nielsen, Sune F. , Butterworth, Adam S. , Ho, Weang Kee , Castagné, Raphaële , Munzel, Thomas , Tregouet, David , Falchi, Mario , Cambien, François , Nordestgaard, Børge G. , Fumeron, Fredéric , Tybjærg-Hansen, Anne , Froguel, Philippe , Danesh, John , Petretto, Enrico , Blankenberg, Stefan , Tiret, Laurence and Richardson, Sylvia
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies (GWAS) yielded significant advances in defining the genetic architecture of complex traits and disease. Still, a major hurdle of GWAS is narrowing down multiple genetic associations to a few causal variants for functional studies. This becomes critical in multi-phenotype GWAS where detection and interpretability of c...
Alternative Titles
Full title
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
Authors, Artists and Contributors
Author / Creator
Chadeau-Hyam, Marc
Hastie, David I.
Zeller, Tanja
Liquet, Benoit
Newcombe, Paul
Yengo, Loic
Wild, Philipp S.
Schillert, Arne
Ziegler, Andreas
Nielsen, Sune F.
Butterworth, Adam S.
Ho, Weang Kee
Castagné, Raphaële
Munzel, Thomas
Tregouet, David
Falchi, Mario
Cambien, François
Nordestgaard, Børge G.
Fumeron, Fredéric
Tybjærg-Hansen, Anne
Froguel, Philippe
Danesh, John
Petretto, Enrico
Blankenberg, Stefan
Tiret, Laurence
Richardson, Sylvia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1433014093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1433014093
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1003657
