Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insig...
Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Opiates are powerful drugs to treat severe pain, and act via mu opioid receptors distributed throughout the nervous system. Their clinical use is hampered by centrally-mediated adverse effects, including nausea or respiratory depression. Here we used a genetic approach to investigate the potential of peripheral mu opioid receptors as targets for pa...
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Full title
Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice
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TN_cdi_plos_journals_1434868403
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1434868403
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0074706
