Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the active site that have distinct binding properties. Moreover, the conformational flexibility of the active site mediates alternative, promiscuous func...
Alternative Titles
Full title
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1435433046
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1435433046
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0075272
