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DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077295

DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

About this item

Full title

DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-10, Vol.8 (10), p.e76299

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Epilepsy is a chronic brain disorder involving recurring seizures often precipitated by an earlier neuronal insult. The mechanisms that link the transient neuronal insult to the lasting state of epilepsy are unknown. Here we tested the possible role of DNA methylation in mediating long-term induction of epileptiform activity by transient kainic aci...

Alternative Titles

Full title

DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1439077295

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077295

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0076299

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