Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival...
Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Doxorubicin (DOX) is a commonly used life-saving antineoplastic agent that also causes dose-dependent cardiotoxicity. Because ATP is absolutely required to sustain normal cardiac contractile function and because impaired ATP synthesis through creatine kinase (CK), the primary myocardial energy reserve reaction, may contribute to contractile dysfunc...
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Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity
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TN_cdi_plos_journals_1439106534
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439106534
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0074675
