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Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439265992

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2

About this item

Full title

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-10, Vol.8 (10), p.e76670

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fumaric acid esters (FAE) are oral analogs of fumarate that have recently been shown to decrease relapse rate and disease progression in multiple sclerosis (MS), prompting to investigate their protective potential in other neurological diseases such as amyotrophic lateral sclerosis (ALS). Despite efficacy in MS, mechanisms of action of FAEs are sti...

Alternative Titles

Full title

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1439265992

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439265992

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0076670

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