A Randomized Pilot Study of L-Arginine Infusion in Severe Falciparum Malaria: Preliminary Safety, Ef...
A Randomized Pilot Study of L-Arginine Infusion in Severe Falciparum Malaria: Preliminary Safety, Efficacy and Pharmacokinetics
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Decreased nitric oxide (NO) and hypoargininemia are associated with severe falciparum malaria and may contribute to severe disease. Intravenous L-arginine increases endothelial NO in moderately-severe malaria (MSM) without adverse effects. The safety, efficacy and pharmacokinetics of L-arginine or other agents to improve NO bioavailability in sever...
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Full title
A Randomized Pilot Study of L-Arginine Infusion in Severe Falciparum Malaria: Preliminary Safety, Efficacy and Pharmacokinetics
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TN_cdi_plos_journals_1440997245
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1440997245
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0069587
