Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Do...
Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Pro-inflammatory activation of vascular endothelium is implicated in pathogenesis of severe conditions including stroke, infarction and sepsis. We have recently reported that superoxide dismutase (SOD) conjugated with antibodies (Ab/SOD) that provide targeted delivery into endothelial endosomes mitigates inflammatory endothelial activation by cytok...
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Full title
Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo
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TN_cdi_plos_journals_1441432692
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1441432692
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077002
