Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of HD patients and mouse disease models. However, the cellular and subcellular sites of iron accumulation, as well as significance to disease progression are not well understoo...
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Full title
Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
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TN_cdi_plos_journals_1441432717
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1441432717
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077023
