Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natura...
Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Protein tyrosine phosphatase B (PtpB) is one of the virulence factors secreted into the host cell by Mycobacterium tuberculosis. PtpB attenuates host immune defenses by interfering with signal transduction pathways in macrophages and, therefore, it is considered a promising target for the development of novel anti-tuberculosis drugs. Here we report...
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Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products
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TN_cdi_plos_journals_1442483982
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1442483982
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077081