Analysis of LGR4 Receptor Distribution in Human and Mouse Tissues
Analysis of LGR4 Receptor Distribution in Human and Mouse Tissues
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Author / Creator
Yi, Jing , Xiong, Wei , Gong, Xing , Bellister, Seth , Ellis, Lee M. and Liu, Qingyun
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
LGR4 is an R-spondin receptor with strong positive effect on Wnt signaling. It plays a critical role in development as its ablation in the mouse led to total embryonic/neonatal lethality with profound defects in multiple organs. Haplotype insufficiency of LGR4 in human was associated with several diseases, including increased risk of squamous cell...
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Full title
Analysis of LGR4 Receptor Distribution in Human and Mouse Tissues
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TN_cdi_plos_journals_1443691297
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1443691297
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0078144