Methylglyoxal evokes pain by stimulating TRPA1
Methylglyoxal evokes pain by stimulating TRPA1
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Diabetic neuropathy is a severe complication of long-standing diabetes and one of the major etiologies of neuropathic pain. Diabetes is associated with an increased formation of reactive oxygen species and the electrophilic dicarbonyl compound methylglyoxal (MG). Here we show that MG stimulates heterologously expressed TRPA1 in CHO cells and native...
Alternative Titles
Full title
Methylglyoxal evokes pain by stimulating TRPA1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1445862163
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1445862163
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077986
