A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition...
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1
About this item
Full title
Author / Creator
Danovi, Davide , Folarin, Amos , Gogolok, Sabine , Ender, Christine , Elbatsh, Ahmed M O , Engström, Pär G , Stricker, Stefan H , Gagrica, Sladjana , Georgian, Ana , Yu, Ding , U, Kin Pong , Harvey, Kevin J , Ferretti, Patrizia , Paddison, Patrick J , Preston, Jane E , Abbott, N Joan , Bertone, Paul , Smith, Austin and Pollard, Steven M
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare responses of human glioblastoma-derived neural stem (GNS) cells and genetically normal neural stem (NS)...
Alternative Titles
Full title
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1
Authors, Artists and Contributors
Author / Creator
Folarin, Amos
Gogolok, Sabine
Ender, Christine
Elbatsh, Ahmed M O
Engström, Pär G
Stricker, Stefan H
Gagrica, Sladjana
Georgian, Ana
Yu, Ding
U, Kin Pong
Harvey, Kevin J
Ferretti, Patrizia
Paddison, Patrick J
Preston, Jane E
Abbott, N Joan
Bertone, Paul
Smith, Austin
Pollard, Steven M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1447630361
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1447630361
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077053
