Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androg...
Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Blocking the androgen receptor (AR) activity is the main goal of therapies for advanced prostate cancer (PCa). However, relapse with a more aggressive, hormone refractory PCa arises, which harbors restored AR activity. One mechanism of such reactivation occurs through acquisition of AR mutations that enable its activation by various steroidal and n...
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Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor
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TN_cdi_plos_journals_1447721927
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1447721927
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0078479
