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Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficie...

Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficie...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1447821985

Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficient mice

About this item

Full title

Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficient mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-11, Vol.8 (11), p.e79395-e79395

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Peripheral axotomy of motoneurons triggers Wallerian degeneration of injured axons distal to the lesion, followed by axon regeneration. Centrally, axotomy induces loss of synapses (synaptic stripping) from the surface of lesioned motoneurons in the spinal cord. At the lesion site, reactive Schwann cells provide trophic support and guidance for outg...

Alternative Titles

Full title

Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficient mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1447821985

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1447821985

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0079395