Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We investigated the effect of Rac-1 and Rho kinase (ROCK) inhibition on progressive renal failure...
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Full title
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease
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TN_cdi_plos_journals_1449332285
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1449332285
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0080328
