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Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-infla...

Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-infla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1450016153

Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-inflammatory action of alcohol

About this item

Full title

Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-inflammatory action of alcohol

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-11, Vol.8 (11), p.e78537

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In the pathogenesis of coronary atherosclerosis, local macrophage-driven inflammation and secretion of proinflammatory cytokines, interleukin-1β (IL-1β) in particular, are recognized as key factors. Moderate alcohol consumption is associated with a reduced risk of coronary artery disease mortality. Here we examined in cultured human macrophages whe...

Alternative Titles

Full title

Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages--a novel anti-inflammatory action of alcohol

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1450016153

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1450016153

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0078537

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