Functional Analysis of Hsp70 Inhibitors
Functional Analysis of Hsp70 Inhibitors
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of Hsp70 proteins exist in cytosol, endoplasmic reticulum and mitochondria, we investigated which isoform needs to be down-regulated for reducing viability of cancer cells. For two recently identified small molecule inhibitor...
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Full title
Functional Analysis of Hsp70 Inhibitors
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TN_cdi_plos_journals_1450248477
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1450248477
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0078443