Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature
Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Pulmonary hypertension (PH) is a serious disorder that causes significant morbidity and mortality. The pathogenesis of PH involves complex derangements in multiple pathways including reductions in peroxisome proliferator-activated receptor gamma (PPARγ). Hypoxia, a common PH stimulus, reduces PPARγ in experimental models. In contrast, activating PP...
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Full title
Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature
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TN_cdi_plos_journals_1458577004
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1458577004
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0079503
