The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Trypanosoma brucei gambiense causes 97% of all cases of African sleeping sickness, a fatal disease of sub-Saharan Africa. Most species of trypanosome, such as T. b. brucei, are unable to infect humans due to the trypanolytic serum protein apolipoprotein-L1 (APOL1) delivered via two trypanosome lytic factors (TLF-1 and TLF-2). Understanding how T. b...
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Full title
The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
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TN_cdi_plos_journals_1458932162
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1458932162
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003686
