Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecul...
Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice
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Author / Creator
Pan, Yong , Zhang, Xiuhua , Wang, Yi , Cai, Lu , Ren, Luqing , Tang, Longguang , Wang, Jingying , Zhao, Yunjie , Wang, Yonggang , Liu, Quan , Li, Xiaokun and Liang, Guang
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Macrophage infiltration contributes to the pathogenesis of diabetic renal injury. However, the regulatory mechanisms between macrophage infiltration and epithelial cell activation are still unclear. Our previous study found that C66, a novel curcumin analog, was able to inhibit inflammatory cytokine expression in vitro and in vivo. This study furth...
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Full title
Targeting JNK by a New Curcumin Analog to Inhibit NF-kB-Mediated Expression of Cell Adhesion Molecules Attenuates Renal Macrophage Infiltration and Injury in Diabetic Mice
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TN_cdi_plos_journals_1459403968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1459403968
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0079084
