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A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1460160824

A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

About this item

Full title

A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-11, Vol.8 (11), p.e81314-e81314

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

β-Sheet-rich aggregates of α-synuclein (αSyn) are the hallmark neuropathology of Parkinson's disease and related synucleinopathies, whereas the principal native structure of αSyn in healthy cells--unfolded monomer or α-helically folded oligomer--is under debate. Our recent crosslinking analysis of αSyn in intact cells showed that a large portion of...

Alternative Titles

Full title

A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1460160824

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1460160824

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0081314

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