Production of Hybrid-IgG/IgA Plantibodies with Neutralizing Activity against Shiga Toxin 1
Production of Hybrid-IgG/IgA Plantibodies with Neutralizing Activity against Shiga Toxin 1
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Shiga toxin 1 (Stx1) is a virulence factor of enterohemorrhagic Escherichia coli, such as the O157:H7 strain. In the intestines, secretory IgA (SIgA) is a major component of the immune defense against pathogens and toxins. To form SIgA, the production of dimeric IgA that retains biological activity is an important step. We previously established hy...
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Production of Hybrid-IgG/IgA Plantibodies with Neutralizing Activity against Shiga Toxin 1
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TN_cdi_plos_journals_1462476240
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1462476240
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0080712