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Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem...

Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1463095068

Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency

About this item

Full title

Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-12, Vol.8 (12), p.e82095-e82095

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exposed to antimycin A, a specific complex III inhibi...

Alternative Titles

Full title

Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1463095068

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1463095068

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0082095

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