Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem...
Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exposed to antimycin A, a specific complex III inhibi...
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Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency
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TN_cdi_plos_journals_1463095068
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1463095068
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0082095