Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression,...
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation, oxidative/nitrosative stress, and cell death. In mdx muscle fibers, we have shown that basal ATP releas...
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Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice
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TN_cdi_plos_journals_1466172800
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1466172800
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0081222
