Hypoxic Tumor Environments Exhibit Disrupted Collagen I Fibers and Low Macromolecular Transport
Hypoxic Tumor Environments Exhibit Disrupted Collagen I Fibers and Low Macromolecular Transport
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Hypoxic tumor microenvironments result in an aggressive phenotype and resistance to therapy that lead to tumor progression, recurrence, and metastasis. While poor vascularization and the resultant inadequate drug delivery are known to contribute to drug resistance, the effect of hypoxia on molecular transport through the interstitium, and the role...
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Full title
Hypoxic Tumor Environments Exhibit Disrupted Collagen I Fibers and Low Macromolecular Transport
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TN_cdi_plos_journals_1467678330
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1467678330
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0081869
