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In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468589785

In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

About this item

Full title

In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2013-11, Vol.9 (11), p.e1003295-e1003295

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Tumour cells show a varying susceptibility to radiation damage as a function of the current cell cycle phase. While this sensitivity is averaged out in an unperturbed tumour due to unsynchronised cell cycle progression, external stimuli such as radiation or drug doses can induce a resynchronisation of the cell cycle and consequently induce a collec...

Alternative Titles

Full title

In Silico Analysis of Cell Cycle Synchronisation Effects in Radiotherapy of Tumour Spheroids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1468589785

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1468589785

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1003295

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