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Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Rou...

Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Rou...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1470558740

Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice

About this item

Full title

Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-12, Vol.8 (12), p.e83933

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

New approaches targeting metastatic neovasculature are needed. Payload capacity, cellular transduction efficiency, and first-pass cellular uptake following systemic vector administration, motivates persistent interest in tumor vascular endothelial cell (EC) adenoviral (Ad) vector targeting. While EC transductional and transcriptional targeting has...

Alternative Titles

Full title

Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1470558740

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1470558740

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0083933

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