Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Rou...
Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
New approaches targeting metastatic neovasculature are needed. Payload capacity, cellular transduction efficiency, and first-pass cellular uptake following systemic vector administration, motivates persistent interest in tumor vascular endothelial cell (EC) adenoviral (Ad) vector targeting. While EC transductional and transcriptional targeting has...
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Transcriptional Targeting of Primary and Metastatic Tumor Neovasculature by an Adenoviral Type 5 Roundabout4 Vector in Mice
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TN_cdi_plos_journals_1470558740
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1470558740
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0083933