HRES-1/Rab4 Promotes the Formation of LC3+ Autophagosomes and the Accumulation of Mitochondria durin...
HRES-1/Rab4 Promotes the Formation of LC3+ Autophagosomes and the Accumulation of Mitochondria during Autophagy
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United States: Public Library of Science
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English
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United States: Public Library of Science
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HRES-1/Rab4 is a small GTPase that regulates endocytic recycling. It has been colocalized to mitochondria and the mechanistic target of rapamycin (mTOR), a suppressor of autophagy. Since the autophagosomal membrane component microtubule-associated protein light chain 3 (LC3) is derived from mitochondria, we investigated the impact of HRES-1/Rab4 on...
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HRES-1/Rab4 Promotes the Formation of LC3+ Autophagosomes and the Accumulation of Mitochondria during Autophagy
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TN_cdi_plos_journals_1473958352
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1473958352
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0084392
