Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synucl...
Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The discovery of the involvement of alpha-synuclein (α-syn) in Parkinson's disease (PD) pathogenesis has resulted in the development and use of viral vector-mediated α-syn overexpression rodent models. The goal of these series of experiments was to characterize the neurodegeneration and functional deficits resulting from injection of recombinant ad...
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Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System
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TN_cdi_plos_journals_1474857490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1474857490
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0081426