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DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1475119783

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

About this item

Full title

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-01, Vol.9 (1), p.e84982

Language

English

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Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with a poor prognosis that is characterized by excessive mitogenic pathway activation and marked chemoresistance to a broad spectrum of chemotherapeutic drugs. Dual specificity protein phosphatase 1 (DUSP1) is a key negative regulator of mitogen activated protein kinases (MAPKs). Yet, DUSP1...

Alternative Titles

Full title

DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1475119783

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1475119783

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0084982

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