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Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's dis...

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's dis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477205976

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease

About this item

Full title

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-01, Vol.9 (1), p.e84349-e84349

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear if specific hippocampal synapses are particularly vulnerable. Since the mossy fiber (MF) synapse...

Alternative Titles

Full title

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1477205976

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477205976

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0084349

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