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Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477954503

Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

About this item

Full title

Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2013-12, Vol.9 (12), p.e1004018-e1004018

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

HoxA genes exhibit central roles during development and causal mutations have been found in several human syndromes including limb malformation. Despite their importance, information on how these genes are regulated is lacking. Here, we report on the first identification of bona fide transcriptional enhancers controlling HoxA genes in developing li...

Alternative Titles

Full title

Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1477954503

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477954503

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004018

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