Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs
Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs
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United States: Public Library of Science
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English
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United States: Public Library of Science
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HoxA genes exhibit central roles during development and causal mutations have been found in several human syndromes including limb malformation. Despite their importance, information on how these genes are regulated is lacking. Here, we report on the first identification of bona fide transcriptional enhancers controlling HoxA genes in developing li...
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Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs
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TN_cdi_plos_journals_1477954503
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1477954503
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1004018