Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cel...
Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Galectin-9 (Gal-9), a lectin having a β-galactoside-binding domain, can induce apoptosis of Th1 cells by binding to TIM-3. In addition, Gal-9 inhibits IgE/Ag-mediated degranulation of mast cell/basophilic cell lines by binding to IgE, thus blocking IgE/Ag complex formation. However, the role of Gal-9 in mast cell function in the absence of IgE is n...
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Full title
Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line
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TN_cdi_plos_journals_1490679769
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490679769
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086106
