Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody A...
Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The urokinase plasminogen activator receptor (uPAR) plays a role in tumor progression and has been proposed as a target for the treatment of cancer. We recently described the development of a novel humanized monoclonal antibody that targets uPAR and has anti-tumor activity in multiple xenograft animal tumor models. This antibody, ATN-658, does not...
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Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)
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TN_cdi_plos_journals_1490992429
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992429
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0085349
