SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of...
SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3
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Full title
Author / Creator
Yin, Songna , Wu, Haibo , Lv, Jiaxing , Wu, Xinying , Zhang, Yan , Du, Juan and Zhang, Yong
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Src-homology protein tyrosine phosphatase-1 (SHP-1) is a protein tyrosine phosphatase that is implicated in the regulation of growth, differentiation, survival, apoptosis and proliferation of hematopoietic cells and other cell types. Here, we found that SHP-1 is involved in regulation of early embryonic development. Embryos overexpressing SHP-1 wer...
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Full title
SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1490992448
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1490992448
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086330
